反应详情

6 g of 2-(6-ethoxybenzothiazol-2-ylthio)-2-phenylpropionic acid ethyl ester and 6 g of KOH in 100 ml of ethanol are stirred at 20°; the mixture is evaporated; the residue is dissolved in water; and the solution is washed with ether, acidified with hydrochloric acid and extracted with CH2Cl2. The phases are separated and the organic phase is dried and evaporated to give 2-(6-ethoxybenzothiazol-2-ylthio)-2-phenylpropionic acid. M.p. 152°-153° (from CCl4).

1. customthe mixture is evaporated
2. dissolutionthe residue is dissolved in water
3. washand the solution is washed with ether
4. extractionextracted with CH2Cl2
5. customThe phases are separated
6. customthe organic phase is dried
7. customevaporated