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Potassium Hydroxide → Tazasubrate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | 2-(6-Ethoxybenzothiazol-2-ylthio)-2-phenylpropionic acid ethyl ester | HCID 12928392 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Tazasubrate | HCID 174749 | — |
反応手順
6 g of 2-(6-ethoxybenzothiazol-2-ylthio)-2-phenylpropionic acid ethyl ester and 6 g of KOH in 100 ml of ethanol are stirred at 20°; the mixture is evaporated; the residue is dissolved in water; and the solution is washed with ether, acidified with hydrochloric acid and extracted with CH2Cl2. The phases are separated and the organic phase is dried and evaporated to give 2-(6-ethoxybenzothiazol-2-ylthio)-2-phenylpropionic acid. M.p. 152°-153° (from CCl4).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04294839 |
| 出典データセット | uspto-grants-1981_10 |
| ORD ID | ord-9e18616d8c23471e9f13d90026eeb3b5 |
| 出典メモ | uspto-grants-1981_10 |