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HRID848156

反应详情

EQUATION

反应方程式

HRID 848156 的结构方程式

REACTANTS

反应物

2
结构：Fc1ccccc1
HCID10008

Fluorobenzene

C6H5F

结构：O=C(O)CCC1CCN(C(=O)c2ccccc2)CC1
HCID19108454

3-(1-Benzoylpiperidin-4-yl)propanoic acid

C15H19NO3

PRODUCTS

生成物

1
结构：O=C(CCC1CCN(C(=O)c2ccccc2)CC1)c1ccc(F)cc1
HCID54515714

3-(1-Benzoyl-4-piperidinyl)-1-(4-fluorophenyl)-1-propanone

C21H22FNO2

收率 125.1%

PROCEDURE

实验过程

The procedure is as in Example 1, starting from 8.8 g of fluorobenzene instead of the 9.9 g of anisol and from 20 g instead of from 15.7 g of 3-(1-benzoyl 4-piperidyl) propionic acid. 25.5 g of crude 3-(1-benzoyl 4-piperidyl) 1-(4-fluorophenyl) 1-propanone in the form of an oil are obtained.