HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fluorobenzene → 3-(1-Benzoyl 4-piperidyl) 1-(4-fluorophenyl) 1-propanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fluorobenzene | HCID 10008 | — |
| Reactant | 3-(1-Benzoylpiperidin-4-yl)propanoic acid | HCID 19108454 | — |
| Product | 3-(1-Benzoyl 4-piperidyl) 1-(4-fluorophenyl) 1-propanone | HCID 54515714 | 125.1% |
Reaction Steps
The procedure is as in Example 1, starting from 8.8 g of fluorobenzene instead of the 9.9 g of anisol and from 20 g instead of from 15.7 g of 3-(1-benzoyl 4-piperidyl) propionic acid. 25.5 g of crude 3-(1-benzoyl 4-piperidyl) 1-(4-fluorophenyl) 1-propanone in the form of an oil are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04294841 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-92c7f755c66c44fb925797974aa488e6 |
| Source note | uspto-grants-1981_10 |