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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 848177Generated: October 31, 2026

Phenyl glycidyl ether → HCID 20566365, compound

https://huagongshe.com/reaction/848177

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl glycidyl etherHCID 31217—
ReactantBenzenamine, 2-((1,2,4-oxadiazol-3-ylmethyl)thio)-HCID 3057622—
ProductHCID 20566365HCID 20566365—

Reaction Steps

A mixture of 3-(2-aminophenylthiomethyl)1,2,4-oxadiazole (2.07 g; 10-2 mol) and 1,2-epoxy-3-phenoxy propane (1.5 g; 10-2 mol) was warmed on a steam bath during 48 hours. The so produced mixture was chromatographed on silica gel, elution with diethyl ether/hexane (1:1) producing 2-hydroxy-1-[2-(1,2,4-oxadiazol-3-yl-methylthio)anilino]-3-phenoxypropane as a colourless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04294843
Source datasetuspto-grants-1981_10
ORD IDord-5dd18a6e32de4b42a97e22bb18fc1e61
Source noteuspto-grants-1981_10