2-Aminothiophenol → HCID 53840238, compound

HRID 848182Notes

Reaction equation

HRID 848182 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[SH:8].[Na].Cl.Cl[CH2:12][C:13](=[N:15][OH:16])[NH2:14]>C(O)C>[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][CH2:12][C:13](=[N:15][OH:16])[NH2:14]

Participants

5

Reactant 3

HCID 87132-AminothiophenolHCID 5360545SodiumHCID 73683878HCID 73683878, compound

Product 1

HCID 53840238HCID 53840238, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Aminobenzenethiol (3.75 g, 0.03 mol) was added to a solution of sodium (0,06 mol, 1.38 g) in ethanol (50 ml). Solid chloroacetamidoxime hydrochloride (4.35 g, 0.03 mol) was added in one portion. After stirring for 10 minutes the reaction mixture was filtered and the filtrate evaporated to dryness to give the crude product which was re-crystallised from iso-propanol to give 2-(2-aminophenylthio) acetamidoxime, m.p. 80°.

Workup

  1. filtrationwas filtered
  2. customthe filtrate evaporated to dryness
  3. customto give the crude product which
  4. customwas re-crystallised from iso-propanol

Sources & evidence

ORD record
ord-bdcb37078c0b4a949a7d43c71085ffca
Source dataset
uspto-grants-1981_10
Patent number
US04294843

Reaction notes

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