反应详情

温度

85 °C

A mixture of 3-chloro-4-(phenethyloxy)aniline (16.06 g; 0.0648 mol), toluene (500 ml) and potassium carbonate (4.5 g; 0.035 mol) is prepared and maintained under nitrogen atmosphere. A. 12.5% solution of phosgene in benzene (65 ml; 0.072 mol) is added to the above mixture. A precipitate forms immediately. The mixture is heated at 85° C. for 45 minutes. By the end of this period the precipitate has dissolved. The reaction mixture is cooled down and filtered. The product is not isolated but rather it is used immediately.

1. customis prepared
2. temperaturemaintained under nitrogen atmosphere
3. dissolutionBy the end of this period the precipitate has dissolved
4. temperatureThe reaction mixture is cooled down
5. filtrationfiltered
6. customThe product is not isolated