Dimethylcarbamoyl Chloride → HCID 20566558, compound

Participants

Reaction Conditions

Reaction Steps

Anhydrous potassium carbonate (10 g) and dimethylcarbamyl chloride (4.0 g; 0.037 mol) are added to a solution of 2-chloro-4-aminophenyl phenethyl sulfide hydrochloride (3.0 g; 0.01 mol) in dry DMF (75 ml) at 25° C. The reaction mixture is heated at 60° C. for 15 hours and then poured into ice water (500 ml). The precipitate (74%) of title product, a white solid, m.p. 133°-134° C.

Provenance & Evidence