HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diazomethane → 1-[3-(acetylthio)-1-oxopropyl]-4-oxo-L-proline, methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diazomethane | HCID 9550 | — |
| Reactant | 1-[3-(Acetylthio)-1-oxopropyl]-4-oxo-L-proline | HCID 12773663 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-[3-(acetylthio)-1-oxopropyl]-4-oxo-L-proline, methyl ester | HCID 12773675 | — |
Reaction Steps
A solution of the product of Example 1 in ether is treated with a slight excess of diazomethane. After standing at room temperature for two hours, the solvent is evaporated to give 1-[3-(acetylthio)-1-oxopropyl]-4-oxo-L-proline, methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04296113 |
| Source dataset | uspto-grants-1981_10 |
| ORD ID | ord-08edb3d9a03a43efba6bc25dad215ea7 |
| Source note | uspto-grants-1981_10 |