Sodium ethoxide → HCID 20565445, compound

HRID 848480Notes

Reaction equation

HRID 848480 reaction equation
Cl[C:2]1[C:7](=[O:8])[N:6]([C:9]2[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=2)[C:5]2[N:16]=[CH:17][CH:18]=[CH:19][C:4]=2[N:3]=1.[O-:20][CH2:21][CH3:22].[Na+]>C(O)C>[CH2:21]([O:20][C:2]1[C:7](=[O:8])[N:6]([C:9]2[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=2)[C:5]2[N:16]=[CH:17][CH:18]=[CH:19][C:4]=2[N:3]=1)[CH3:22]

Participants

4

Reactant 2

HCID 2723922Sodium ethoxideHCID 20565460HCID 20565460, compound

Product 1

HCID 20565445HCID 20565445, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Preparation as in Example 26 but using 2-chloro-3,4-dihydro-4-(4-methylphenyl)-3-oxopyrido[2,3-b]pyrazine and sodium ethoxide in ethanol gave the title compound which was identified by NMR Delta 1.50 (t) 3H, delta 2.43 (s) 3H, delta 4.59 (q) 2H, delta 7.05-7.45 (m) 5H, delta 7.91 (q) 1H, delta 8.27 (q) 1H.

Workup

  1. customPreparation as in Example 26

Sources & evidence

ORD record
ord-fd16ba02e27b43cf8fb7cc461a7031a9
Source dataset
uspto-grants-1981_10
Patent number
US04296114

Reaction notes

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