2,4,5,6(1H,3H)-Pyrimidinetetrone, monohydrate → HCID 56633917, compound

HRID 848486Notes

Reaction equation

HRID 848486 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10]2[C:11]([NH2:16])=[CH:12][CH:13]=[CH:14][CH:15]=2)=[CH:5][CH:4]=1.O.N1C(=O)[C:24](=O)[C:22](=[O:23])NC1=O>C(O)C.O>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([N:9]2[C:10]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[N:16]=[CH:24][C:22]2=[O:23])=[CH:7][CH:8]=1

Participants

5

Reactant 2

HCID 167232,4,5,6(1H,3H)-Pyrimidinetetrone, monohydrateHCID 3837384HCID 3837384, compound

Product 1

HCID 56633917HCID 56633917, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

To a solution of N-(4-methoxyphenyl)benzene-1,2-diamine (9.0 g) in ethanol (150 ml) was added a solution of alloxan monohydrate (6.7 g) in water (150 ml) and the mixture was stirred for 30 minutes. The precipitate was filtered off and recrystallised from glacial acetic acid giving the title compound mp 236°-238° C.

Workup

  1. filtrationThe precipitate was filtered off
  2. customrecrystallised from glacial acetic acid giving the title compound mp 236°-238° C.

Sources & evidence

ORD record
ord-62625e2fe9614868958e51327dbb292d
Source dataset
uspto-grants-1981_10
Patent number
US04296114

Reaction notes

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