反应详情

Methyl 2-methyl-5-nitrobenzyl ether (11.5 g) was dissolved in 125 ml of absolute ethanol. To this was added a solution of sodium sulfide monohydrate (48.3 g) and sodium bicarbonate (16.7 g) in 75 ml of water. The resulting mixture was refluxed until tlc indicated all the starting material was gone. The mixture was then concentrated in vacuo to an oily solid. Methylene chloride was added and the mixture filtered. The methylene chloride layer was separated and dried. After removal of the drying agent, the solvent was concentrated in vacuo to give 9.3 g of a mobile orange liquid,

1. temperatureThe resulting mixture was refluxed
2. concentrationThe mixture was then concentrated in vacuo to an oily solid
3. additionMethylene chloride was added
4. filtrationthe mixture filtered
5. customThe methylene chloride layer was separated
6. customdried
7. customAfter removal of the drying agent
8. concentrationthe solvent was concentrated in vacuo