Hydrochloric Acid → HCID 178516179, compound

Participants

Reaction Steps

5.6 g (0.02 mole) of pGlu-His-OMe are dissolved in 200 cc of MeOH and treated while cold for 2 hours with 4.8 g (6×0.02 mole) of NaOH. The solution which is obtained is acidified to pH 4.5 with 6×0.02 mole of HCl. After being evaporated to dryness under vacuum at 50° C., the pGlu-His-OH is obtained, and this can be used without any additional purification. White solid; yield is quantitative.

Provenance & Evidence