Potassium Carbonate → HCID 11077341, compound

HRID 849011Notes

Reaction equation

HRID 849011 reaction equation
[O:1]=[C:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[CH2:5][O:4][NH:3]1.Br[CH2:13][CH2:14][O:15][C:16]1[CH:23]=[CH:22][C:19]([CH:20]=[O:21])=[CH:18][CH:17]=1.C([O-])([O-])=O.[K+].[K+]>>[O:1]=[C:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[CH2:5][O:4][N:3]1[CH2:13][CH2:14][O:15][C:16]1[CH:23]=[CH:22][C:19]([CH:20]=[O:21])=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 2627064-(2-Bromoethoxy)BenzaldehydeHCID 13557284HCID 13557284, compound

Product 1

HCID 11077341HCID 11077341, compoundYield 66.6%

Procedure

##STR34## The title compound (370 mg, 66%) was prepared from 4-oxo-3,4-dihydro-1H-2,3-benzoxazine (280 mg, 1.87 mmol) (prepared according to the procedure described in Tetrahedron, 22 (1966) 2107) and 4-(2-bromoethoxy)benzaldehyde (430 mg, 1.87 mmol) and K2CO3 (520 mg, 3.74 mmol). mp: 102° C.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-9abe455b130b4a5087a85a3c5edb7721
Source dataset
uspto-grants-2000_01
Patent number
US06011036

Reaction notes

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