Water → HCID 12813906, compound

Participants

Reaction Steps

Example 290 A) A sample of 1-Pyrrolidino-1-cyclohexene (7.1 mL, 44 mmol) and 2-vinylpyridine (4.3 mL, 40 mmol) were refluxed overnight in diglyme (100 mL). Water was then added and the mixture was stirred an additional 2 hours before extracting it with Et2O. The ether layer was dried over MgSO4 and concentrated in vacuo leaving an oil. The residue oil was distilled on a kugelrohr apparatus at 60-80° C. (0.1 mm) to give 2-(2-pyridyl) ethyl-2-cyclohexanone as a yellow oil (6.5 g).

Provenance & Evidence