4-Amino-1-butanol → HCID 19369833, compound

Participants

Reaction Steps

1-(2-Methoxyphenyl)-4-chloro-6-β,β,β-trifluoroethoxy-2,3-dihydropyrrolo[3,2-c]quinoline(500 mg, 1.2 mmol) was dissolved in diethylene glycol(10 ml) and 4-amino-1-butanol(175 μl, 1.9 mmol) was added. It was reacted at the same condition of Step 3 in the Example 38 to obtain 120 mg of desired compound as solid in 39% of yield.

Provenance & Evidence