HRID849230

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7498

alpha-Bromotoluene

C7H7Br

HCID15614003

Ethyl 6-(chloromethyl)pyridine-2-carboxylate

C9H10ClNO2

结构：C=CCOC(=O)Nc1cccc(CNc2cc(N3CCOCC3)cc(C(C)Sc3nnc(CC)s3)n2)c1

HCID19369555

未命名化合物

PRODUCTS

生成物

结构：C=CCOC(=O)Nc1cccc(CNc2cc(N3CCOCC3)cc(CSc3nnc(CC)s3)n2)n1

HCID19369722

未命名化合物

PROCEDURE

实验过程

The above identified compound was obtained as a pale yellow solid in the same manner as in Example 1-(6), Example 4-(2) and (3) and Example 1-(7) except that benzyl bromide was changed to ethyl 6-chloromethylpyridine-2-carboxylate.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-882efe6d3d154f0697354f081212610a
来源数据集: uspto-grants-2000_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06011039
来源说明: uspto-grants-2000_01

反应 SMILES

[CH2:1]([C:3]1[S:7][C:6]([S:8][CH:9]([C:11]2[N:16]=[C:15]([NH:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[C:21]([NH:25][C:26]([O:28][CH2:29][CH:30]=[CH2:31])=[O:27])C=3)[CH:14]=[C:13]([N:32]3[CH2:37][CH2:36][O:35][CH2:34][CH2:33]3)[CH:12]=2)C)=[N:5][N:4]=1)[CH3:2].C(Br)C1C=CC=CC=1.ClCC1[N:53]=C(C(OCC)=O)C=CC=1>>[CH2:1]([C:3]1[S:7][C:6]([S:8][CH2:9][C:11]2[N:16]=[C:15]([NH:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[C:21]([NH:25][C:26]([O:28][CH2:29][CH:30]=[CH2:31])=[O:27])[N:53]=3)[CH:14]=[C:13]([N:32]3[CH2:33][CH2:34][O:35][CH2:36][CH2:37]3)[CH:12]=2)=[N:5][N:4]=1)[CH3:2]