huagongshe.com
HRID849294

反应详情

EQUATION

反应方程式

HRID 849294 的结构方程式

REACTANTS

反应物

1
结构：CCOC(=O)Cn1c(=O)c([N+](=O)[O-])cn(COC)c1=O
HCID21355699

Ethyl 3,6-dihydro-3-(methoxymethyl)-5-nitro-2,6-dioxo-1(2H)-pyrimidineacetate

C10H13N3O7

PRODUCTS

生成物

1
结构：CCOC(=O)Cn1c(=O)c(N)cn(COC)c1=O
HCID54496358

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A stirred solution of the compound of Example 42 (10.0 g, 35 mmole) in ethanol (100 mL) is hydrogenated over 10% Pd/C (1.00 g) for 8 hours under balloon pressure. Celite is added, and the reaction mixture is filtered through a pad of celite, using ethyl acetate to wash. The solvent is removed in vacuo to give crude ethyl 5-amino-1-methoxymethyl-uracilylacetate.

WORKUP

后处理

  1. additionCelite is added
  2. filtrationthe reaction mixture is filtered through a pad of celite
  3. washto wash
  4. customThe solvent is removed in vacuo