HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 178478877, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 7-Bromo-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-4-(1-naphthalenylcarbonyl)-1H-1,4-benzodiazepine, hydrochloride | HCID 178479667 | — |
| Product | HCID 178478877 | HCID 178478877 | — |
Reaction Steps
Example 274 was prepared as an off white solid from Compound B as described for Compound F of Example 41, with chromatography using 5% MeOH/0.5% NH4OH/methylene chloride, and Compound D of Example 1, with purification by prep HPLC before formation of the HCl salt. MS (M+H) 413.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06011029 |
| Source dataset | uspto-grants-2000_01 |
| ORD ID | ord-5b56f5ea2088444ca8e2d886391574cd |
| Source note | uspto-grants-2000_01 |