HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Thiophenesulfonyl chloride → HCID 178478901, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Thiophenesulfonyl chloride | HCID 85518 | — |
| Reactant | (R)-7-Bromo-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-4-(methylsulfonyl)-3-(phenylmethyl)-1H-1,4-benzodiazepine, hydrochloride | HCID 178504910 | — |
| Reactant | HCID 178504911 | HCID 178504911 | — |
| Product | HCID 178478901 | HCID 178478901 | — |
Reaction Steps
Example 329 was prepared as an off white solid from (R)-2,3,4,5-tetrahydro-7-phenyl-3-(3-pyridinylmethyl)-1H-1,4-benzodiazepine (prepared as described in Example 273) and 2-thiophenesulfonyl chloride by the following sequence: Compound C of Example 224; Compound D of Example 224. MS (M+H)+ 542.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06011029 |
| Source dataset | uspto-grants-2000_01 |
| ORD ID | ord-c6b19c35c69144c6abfe590a79184ed3 |
| Source note | uspto-grants-2000_01 |