HCID 19365451, compound → 4-Amino-2-(2-ethylhexanoylamino)-phenol

HRID 849902Notes

Reaction equation

HRID 849902 reaction equation
[CH2:1]([CH:3]([CH2:17][CH2:18][CH2:19][CH3:20])[C:4]([NH:6][C:7]1[CH:12]=[C:11]([N+:13]([O-])=O)[CH:10]=[CH:9][C:8]=1[OH:16])=[O:5])[CH3:2]>C(O)C.[H][H].[Ni]>[NH2:13][C:11]1[CH:10]=[CH:9][C:8]([OH:16])=[C:7]([NH:6][C:4](=[O:5])[CH:3]([CH2:1][CH3:2])[CH2:17][CH2:18][CH2:19][CH3:20])[CH:12]=1

Participants

4

Reactant 1

HCID 19365451HCID 19365451, compound

Product 1

HCID 193654504-Amino-2-(2-ethylhexanoylamino)-phenol

Reagents, catalysts & solvents 2

HCID 178506447HCID 178506447, compoundCatalystHCID 702EthanolSolvent

Procedure

39 g of preliminary product 1 were hydrogenated with H2 /Raney nickel in 200 ml ethanol. The hydrogenation was conducted over a period of 2 hours and within a temperature range from 20 to 40 C. at a pressure of 2. 106Pa. The catalyst was filtered off under suction and 400 ml water were added. The dried, oily product (37 g) which was separated was reacted further without additional purification.

Workup

  1. filtrationThe catalyst was filtered off under suction and 400 ml water
  2. additionwere added
  3. customThe dried, oily product (37 g) which was separated
  4. customwas reacted further without additional purification

Sources & evidence

ORD record
ord-a5a347101d3b4423bfa31a74ff8dece9
Source dataset
uspto-grants-2000_01
Patent number
US06015654

Reaction notes

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