Bromine → HCID 19365867, compound

HRID 850028Notes

Reaction equation

HRID 850028 reaction equation
[S:1]1[C:9]2[CH2:8][CH2:7][NH:6][CH2:5][C:4]=2[CH:3]=[CH:2]1.[Br:10]Br>C(Cl)(Cl)Cl>[BrH:10].[Br:10][C:2]1[S:1][C:9]2[CH2:8][CH2:7][NH:6][CH2:5][C:4]=2[CH:3]=1

Participants

4

Reactant 2

HCID 24408BromineHCID 30850764,5,6,7-Tetrahydrothieno(3,2-c)pyridine

Product 1

HCID 19365867HCID 19365867, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The product from Step 1 (9.57 g, 40 mmol) was dissolved in CHCl3 (150 mL) at 0° C. and treated with bromine (2.1 mL, 40 mmol) dropwise over 10 minutes. The mixture was stirred for 16 h at room temperature then filtered to afford the title compound as a solid.

Workup

  1. filtrationthen filtered

Sources & evidence

ORD record
ord-23487d2a2ad94b66bfb21a72b64a3eb3
Source dataset
uspto-grants-2000_01
Patent number
US06015817

Reaction notes

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