Cyclohexyl bromide → Ethyl 1-(3-cyano-4-cyclohexyloxyphenyl)pyrazole-4-carboxylate

HRID 850075Notes

Reaction equation

HRID 850075 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([N:10]2[CH:14]=[C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:12]=[N:11]2)[CH:6]=[CH:7][C:8]=1[OH:9])#[N:2].[CH:20]1(Br)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1>>[C:1]([C:3]1[CH:4]=[C:5]([N:10]2[CH:14]=[C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:12]=[N:11]2)[CH:6]=[CH:7][C:8]=1[O:9][CH:20]1[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1)#[N:2]

Participants

3

Reactant 2

HCID 7960Cyclohexyl bromideHCID 15407383Ethyl 1-(3-cyano-4-hydroxyphenyl)pyrazole-4-carboxylate

Product 1

HCID 19366035Ethyl 1-(3-cyano-4-cyclohexyloxyphenyl)pyrazole-4-carboxylate

Procedure

The same reaction and treatment as in Example 5 using ethyl 1-(3-cyano-4-hydroxyphenyl)pyrazole-4-carboxylate and cyclohexyl bromide gives ethyl 1-(3-cyano-4-cyclohexyloxyphenyl)pyrazole-4-carboxylate.

Sources & evidence

ORD record
ord-db4b53bc5d214d30a9a94021cb16431f
Source dataset
uspto-grants-2000_01
Patent number
US06015829

Reaction notes

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