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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 850111Generated: October 30, 2026

alpha-Bromo-o-fluorotoluene → 2-(2-Fluorophenyl)-4'-iodoacetophenone

https://huagongshe.com/reaction/850111

Reaction equation

Participants

RoleNameHCIDCharge
Reactantalpha-Bromo-o-fluorotolueneHCID 67968—
Reactant4-Iodo-N-methoxy-N-methyl-benzamideHCID 5461756—
Product2-(2-Fluorophenyl)-4'-iodoacetophenoneHCID 19365939—

Reaction Steps

The product was prepared from 2-fluorobenzyl bromide and O,N-dimethyl-4-iodobenzenehydroxamic acid (see Preparation 30) by a similar method to Preparation 20(i) as a colourless solid, m.p. 112-114° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06015825
Source datasetuspto-grants-2000_01
ORD IDord-20e099695ebc4c4d92f9fbd0a7999eca
Source noteuspto-grants-2000_01