3-(Aminomethyl)biphenyl → HCID 86755084, compound

HRID 850211Notes

Reaction equation

HRID 850211 reaction equation
C1(C2C=C(C=CC=2)CN)C=CC=CC=1.[CH3:15][C:16]([CH3:38])([CH3:37])[C:17]#[C:18]/[CH:19]=[CH:20]/[CH2:21][N:22]([CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[C:27]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH:26]=1)[CH3:23]>>[CH3:15][C:16]([CH3:38])([CH3:37])[C:17]#[C:18]/[CH:19]=[CH:20]\[CH2:21][N:22]([CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[C:27]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[CH:26]=1)[CH3:23]

Participants

3

Reactant 2

HCID 27603683-(Aminomethyl)biphenylHCID 9797048HCID 9797048, compound2×

Product 1

HCID 86755084HCID 86755084, compound

Procedure

3-Phenylbenzylamine (3.93 g) was processed in a similar manner as in Synthesis Example 5, whereby trans-N-(6,6-dimethyl-2-hepten-4-yn-1-yl)-N-methyl-3-phenylbenzylamine (Compound 7) and cis-N-(6,6-dimethyl-2-hepten-4-yn-1-yl)-N-methyl-3-phenylbenzylamine (Compound 8) were obtained in amounts of 2.73 g (yield: 45%) and 0.72 g (yield: 11.9%), respectively. The followings are their NMR spectrum data:

Sources & evidence

ORD record
ord-9e150c863a6b4254adc9879f789e8ee6
Source dataset
uspto-grants-2000_01
Patent number
US06015925

Reaction notes

Loading…