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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 850340Generated: October 29, 2026

Morpholine → (3,5-Di-tert-butyl-4-hydroxy-phenyl)-(N-morpholinyl)-acetic acid ethyl ester

https://huagongshe.com/reaction/850340

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantEthyl 2-bromo-(3,5-di-t-butyl-4-hydroxyphenyl)-acetateHCID 12018252—
Product(3,5-Di-tert-butyl-4-hydroxy-phenyl)-(N-morpholinyl)-acetic acid ethyl esterHCID 9907750—

Reaction Steps

The compound was synthesized as in Example 17 from Intermediate 11 (4.0 g, 10.8 mmol) and morpholine (2.1 g, 24 mmol). This gave 0.91 g (22%) of pure product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06017918
Source datasetuspto-grants-2000_01
ORD IDord-40e334e316c7438fa2913d9309b1bc00
Source noteuspto-grants-2000_01