tert-Butyl methyl ether → Acetone cyclohexane
Reaction equation
N[CH2:2]/[CH:3]=[CH:4]/[CH:5]=[CH2:6].[CH3:7][C:8]([O:11]C)(C)[CH3:9]>>[CH2:2]1[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.[CH3:7][C:8]([CH3:9])=[O:11]Participants
3
Procedure
Initially introduce 83.2 g (1.0 mol) of (E)-1-amino-2,4-pentadiene (title compound from Example B.2.) in 250 ml of MTBE, and add 0.1 g of 4-hydroxyanisole. Subsequently, at an internal temperature of 20-30° C., add 229.2 g (1.05 mol) of di-tert-butyl dicarbonate dissolved in 250 ml of MTBE dropwise. After addition is complete, stir at room temperature for 20 h. Concentrate the reaction 10 mixture and take up in 1 l of toluene. Add 103.0 g (1.05 mol) of maleic anhydride, and stir at an internal temperature of 60° C. for 24 h. Filter off the precipitate with suction, wash it with toluene and dry it at 50° C. to constant weight.
Sources & evidence
- ORD record
- ord-5ed2831c9b0b4d6f803c706bb5696cfe
- Source dataset
- uspto-grants-2000_01
- Patent number
- US06018054
Reaction notes
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