反应详情

To a solution of 8.6 g. of ethyl 5-amino-2-thiophenecarboxylate and 25 ml. of triethylamine in 100 ml. of methylene chloride is added dropwise 16.5 g. of palmitoyl chloride. The reaction mixture is stirred for 20 hours. Evaporation affords an oil. A methylene chloride solution of the oil is filtered and the filtrate passed through Magnesol. Removal of the solvent by evaporation yields a solid which is recrystallized from hexane. A second recrystallization from carbon tetrachloride affords the product.

1. customEvaporation
2. customaffords an oil
3. filtrationA methylene chloride solution of the oil is filtered
4. customRemoval of the solvent
5. customby evaporation
6. customyields a solid which
7. customis recrystallized from hexane
8. customA second recrystallization from carbon tetrachloride
9. customaffords the product