反应详情

A mixture of 0.1 g. of ethyl 5-hexadecylamino-2-thiophenecarboxylate, 10 ml. of absolute ethanol and 10 ml. of 0.5 N sodium hydroxide is refluxed for 3 hours. The reaction mixture is cooled and then concentrated. The pH of the solution is adjusted to 5.3 and the resulting solid filtered and dried to yield the product.

1. additionA mixture of 0.1 g
2. temperatureThe reaction mixture is cooled
3. concentrationconcentrated
4. filtrationthe resulting solid filtered
5. customdried
6. customto yield the product