反应详情

To a solution of 39 g. of 5-nitro-2-furancarboxylic acid in 200 ml. of ethanol is added 2 ml. of p-toluenesulfonic acid. The reaction is heated for 48 hours. The reaction mixture is evaporated and methylene chloride is added to the residue. The solution is extracted with 10% sodium bicarbonate and dried over anhydrous sodium sulfate. The solution is concentrated and then filtered through Magnesol. The product is obtained by recrystallization from methylene chloride and hexane.

1. temperatureThe reaction is heated for 48 hours
2. customThe reaction mixture is evaporated
3. additionmethylene chloride is added to the residue
4. extractionThe solution is extracted with 10% sodium bicarbonate
5. dry with materialdried over anhydrous sodium sulfate
6. concentrationThe solution is concentrated
7. filtrationfiltered through Magnesol
8. customThe product is obtained by recrystallization from methylene chloride and hexane