Hydrochloric Acid → HCID 20502541, compound

Participants

Reaction Steps

To a solution of 1-[3-(4-trityl-1-piperazinyl)propyl]isatin (5.0 g) in tetrahydrofuran (100 ml) was added all at once concentrated hydrochloric acid (5 ml) and the mixture was vigorously stirred for half an hour. The resultant precipitates were collected by filtration and washed with tetrahydrofuran to give 1-[3-(1-piperazinyl)propyl]isatin dihydrochloride (2.96 g).

Provenance & Evidence