HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenacyl bromide → 1-Phenyl-2-[3-(3-methoxyphenyl)-1,2,5,6-tetrahydropyridin-1-yl]-ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenacyl bromide | HCID 6259 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-(3-Methoxyphenyl)-1,2,5,6-tetrahydropyridine hydrochloride | HCID 13066749 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-Phenyl-2-[3-(3-methoxyphenyl)-1,2,5,6-tetrahydropyridin-1-yl]-ethanone | HCID 20502635 | 102.8% |
Reaction Steps
A mixture of 10 g of 3-(3-methoxyphenyl)-1,2,5,6-tetrahydropyridine hydrochloride, 200 ml of acetone, 14 g of sodium carbonate and 9.3 g of phenacyl bromide were refluxed for 3 hours and was filtered. The filtrate was evaporated to dryness to obtain 14 g of 1-phenyl-2-[3-(3-methoxyphenyl)-1,2,5,6-tetrahydropyridin-1-yl]-ethanone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04382942 |
| Source dataset | uspto-grants-1983_05 |
| ORD ID | ord-bc57e7602f544336bcb77a7bb923f307 |
| Source note | uspto-grants-1983_05 |