HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 851149Generated: October 29, 2026
Methyl Isocyanate → N-methyl-carbamic acid O-(1-iso-propylpyrazol-4-yl) ester
https://huagongshe.com/reaction/851149
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 1-(Propan-2-yl)-1H-pyrazol-4-ol | HCID 13018411 | — |
| Catalyst | Triethylamine | HCID 8471 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | N-methyl-carbamic acid O-(1-iso-propylpyrazol-4-yl) ester | HCID 13018414 | 95% |
Reaction Steps
6 g (0.105 mol) of methyl isocyanate were added to a solution of 12.6 g (0.1 mol) of 1-isopropyl-4-hydroxy-pyrazole in 100 ml of acetone and 2 drops of triethylamine. The mixture was stirred at 45° C. for 12 hours and the solvent was then distilled off in vacuo. 17.4 g (95% of theory) of N-methyl-carbamic acid O-(1-iso-propylpyrazol-4-yl) ester were thus obtained in the form of beige crystals with a melting point of 40° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04382947 |
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| Source dataset | uspto-grants-1983_05 |
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| ORD ID | ord-d3a9672dd9d346b18070dfedfc708c8a |
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| Source note | uspto-grants-1983_05 |
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