HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol, 3-(1,1-dimethylethyl)- → 8-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol, 3-(1,1-dimethylethyl)- | HCID 11450 | — |
| Reactant | Methyl 4-oxopiperidine-3-carboxylate hydrochloride | HCID 2724028 | — |
| Product | 8-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-one | HCID 13136921 | 57.1% |
Reaction Steps
Prepared by the method described for Example 1 from 3-t-butylphenol (15 g, 0.1 moles) and methyl 4-oxo-3-piperidinecarboxylate hydrochloride (19.3 g, 0.1 moles). Recrystallization from ethyl acetate gave the product (14.7 g), mp 181°-186° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04382939 |
| Source dataset | uspto-grants-1983_05 |
| ORD ID | ord-64348656756e474b9b39a0f55fc8c9f7 |
| Source note | uspto-grants-1983_05 |