HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetone → 1,2,3,4-Tetrahydro-8-methoxy-9-nitro-3-(2-oxopropyl)-5H-[1]benzo-pyrano[3,4-c]pyridin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetone | HCID 6571 | — |
| Reactant | 1,2,3,4-Tetrahydro-8-methoxy-9-nitro-5H-[1]benzopyrano[3,4-c]pyridin-5-one | HCID 13136925 | — |
| Product | 1,2,3,4-Tetrahydro-8-methoxy-9-nitro-3-(2-oxopropyl)-5H-[1]benzo-pyrano[3,4-c]pyridin-5-one | HCID 13136939 | 85.8% |
Reaction Steps
Prepared by the method described for Example 26 from 1,2,3,4-tetrahydro-8-methoxy-9-nitro-5H-[1]benzopyrano[3,4-c]pyridin-5-one (5.52 g, 0.02 moles) and 1-chloro-2-propanone (3.5 g, 0.038 moles). Recrystallization from methanol gave the product (5.7 g), mp 222°-225° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04382939 |
| Source dataset | uspto-grants-1983_05 |
| ORD ID | ord-2cf31350f6c64d238cbed128d7da28b1 |
| Source note | uspto-grants-1983_05 |