HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 3-[2-(Dimethylamino)propyl]-1,2,3,4-tetrahydro-8,9-dimethyl-5H-[1]benzopyrano[3,4-c]pyridin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 1,2,3,4-Tetrahydro-8,9-dimethyl-3-(2-oxopropyl)-5H-[1]benzopyrano[3,4-c]pyridin-5-one | HCID 13136931 | — |
| Product | 3-[2-(Dimethylamino)propyl]-1,2,3,4-tetrahydro-8,9-dimethyl-5H-[1]benzopyrano[3,4-c]pyridin-5-one | HCID 13136954 | 8.6% |
Reaction Steps
Prepared by the method described in Example 38 from 1,2,3,4-tetrahydro-8,9-dimethyl-3-(2-oxopropyl)-5H-[1]benzopyrano[3,4-c]pyridin-5-one (7.3 g, 0.026 moles) and dimethylamine (10.0 g, 0.22 moles). Several recrystallizations from acetonitrile yielded the product as the free base (0.7 g) mp 105°-107° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04382939 |
| Source dataset | uspto-grants-1983_05 |
| ORD ID | ord-ea8f689b617c48e9bee41639cff4bc97 |
| Source note | uspto-grants-1983_05 |