Ethylamine → HCID 13136975, compound

HRID 851218Notes

Reaction equation

HRID 851218 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]2[C:9]3[CH2:14][CH2:13][N:12]([CH2:15][C:16](=O)[CH3:17])[CH2:11][C:10]=3[C:19](=[O:21])[O:20][C:5]=2[CH:4]=1.[CH2:22]([NH2:24])[CH3:23]>>[CH2:22]([NH:24][CH:16]([CH3:17])[CH2:15][N:12]1[CH2:13][CH2:14][C:9]2[C:6]3[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][C:5]=3[O:20][C:19](=[O:21])[C:10]=2[CH2:11]1)[CH3:23]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 13136938HCID 13136938, compound

Product 1

HCID 13136975HCID 13136975, compoundYield 43.2%

Procedure

Prepared by the method described for Example 51 from 1,2,3,4-tetrahydro-8-methoxy-3-(2-oxopropyl)-5H-[1]benzopyrano[3,4-c]pyridin-5-one (14.9 g, 0.052 moles) and ethylamine (5 ml, 0.07 moles). Recrystallization from ethyl acetate gave the product (7.1 g), mp 97°-100° C.

Workup

  1. customPrepared by the method
  2. customRecrystallization from ethyl acetate

Sources & evidence

ORD record
ord-dac2817311dc47528dd4037f64b6ec54
Source dataset
uspto-grants-1983_05
Patent number
US04382939

Reaction notes

Loading…