Hydrogen Bromide → HCID 13137007, compound

HRID 851230Notes

Reaction equation

HRID 851230 reaction equation
Cl.Cl.[CH2:3]([N:5]([CH2:28][CH3:29])[CH:6]([CH3:27])[CH2:7][N:8]1[CH2:13][CH2:12][C:11]2[C:14]3[CH:22]=[C:21]([O:23]C)[C:20]([O:25]C)=[CH:19][C:15]=3[O:16][C:17](=[O:18])[C:10]=2[CH2:9]1)[CH3:4].[BrH:30]>>[BrH:30].[BrH:30].[CH2:28]([N:5]([CH2:3][CH3:4])[CH:6]([CH3:27])[CH2:7][N:8]1[CH2:13][CH2:12][C:11]2[C:14]3[CH:22]=[C:21]([OH:23])[C:20]([OH:25])=[CH:19][C:15]=3[O:16][C:17](=[O:18])[C:10]=2[CH2:9]1)[CH3:29]

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 13136997HCID 13136997, compound

Product 1

HCID 13137007HCID 13137007, compound

Procedure

Prepared by the method described in Example 36 from 3-[2-(diethylamino)propyl]-1,2,3,4-tetrahydro-8,9-dimethoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one dihydrochloride (23.3 g, 0.052 moles) and 48% aqueous hydrobromic acid (200 ml). After washing several times with cold acetone, the product (25.0 g, mp 257°-258° C.) is used as an intermediate without additional purification.

Workup

  1. customPrepared by the method
  2. washAfter washing several times with cold acetone
  3. customthe product (25.0 g, mp 257°-258° C.) is used as an intermediate without additional purification

Sources & evidence

ORD record
ord-1e47786e2a864eeba95cde1a61e992a6
Source dataset
uspto-grants-1983_05
Patent number
US04382939

Reaction notes

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