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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 851479Generated: October 30, 2026

Sodium Carbonate → HCID 135672568, compound

https://huagongshe.com/reaction/851479

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CarbonateHCID 10340—
Reactant4-HydroxythiobenzamideHCID 2759344—
ReactantHCID 78246224HCID 78246224—
SolventIsopropanolHCID 3776—
ProductHCID 135672568HCID 135672568—

Reaction Steps

3-Bromo-3-(4-chlorobenzoyl)propionate acid and an equimolar amount of 4-hydroxythio-benzamide are stirred in isopropyl alcohol solvent containing sodium carbonate to give 4-(4-chlorophenyl)-4-hydroxy-2-(4-hydroxyphenyl)-2-thiazolin-5-acetic acid. This compound is dehydrated by heating to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04385059
Source datasetuspto-grants-1983_05
ORD IDord-7b91b82d317b4956a83fd968adaea952
Source noteuspto-grants-1983_05