HCID 20430894, compound → HCID 53844146, compound

HRID 851509Notes

Reaction equation

HRID 851509 reaction equation
[CH3:1][C:2]1([CH3:10])[CH2:6][CH2:5][C:4]([C:7]([OH:9])=[O:8])=[CH:3]1.[C:11]([OH:19])(=[S:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>C1CCCCC1>[C:11]([S:18][C@@H:3]1[C:2]([CH3:10])([CH3:1])[CH2:6][CH2:5][C@H:4]1[C:7]([OH:9])=[O:8])(=[O:19])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 20430894HCID 20430894, compoundHCID 178526132HCID 178526132, compound

Product 1

HCID 53844146HCID 53844146, compoundYield 51.6%

Reagents, catalysts & solvents 1

HCID 8078CyclohexaneSolvent

Conditions

Temperature
120 °C

Procedure

A mixture of 3,3-dimethyl-1-cyclopentene-1-carboxylic acid (2 g) and thio-benzoic acid (2.37 g) is heated to 120° C. for 14 hours under Argon stream. The reaction mixture is cooled, taken up with a small amount of cyclohexane and filtered yielding 2.05 g of trans 2-benzoylthio-3,3-dimethylcyclopentyl carboxylic acid. M.p. 131° C. (from hexane).

Workup

  1. temperatureThe reaction mixture is cooled
  2. filtrationfiltered

Sources & evidence

ORD record
ord-902c74537d8d490f818a74c20674e96e
Source dataset
uspto-grants-1983_05
Patent number
US04385062

Reaction notes

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