Diethylamine → 2-Cyanoethyl trans-3-diethylaminoacrylate

HRID 851532Notes

Reaction equation

HRID 851532 reaction equation
[C:1]([O:5][CH2:6][CH2:7][C:8]#[N:9])(=[O:4])[C:2]#[CH:3].[CH2:10]([NH:12][CH2:13][CH3:14])[CH3:11]>C(Cl)(Cl)Cl>[CH2:10]([N:12]([CH2:13][CH3:14])/[CH:3]=[CH:2]/[C:1]([O:5][CH2:6][CH2:7][C:8]#[N:9])=[O:4])[CH3:11]

Participants

4

Reactant 2

HCID 8021DiethylamineHCID 204932242-Cyanoethyl prop-2-ynoate

Product 1

HCID 204932262-Cyanoethyl trans-3-diethylaminoacrylate

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent3×

Procedure

A solution of 48 g (0.39 moles) of 2-cyanoethyl propiolate in 100 ml of chloroform was treated with a solution of 28.5 g (0.38 moles) of diethylamine in 100 ml of chloroform. The temperature was kept at 10° to 20° C. during the addition. The chloroform was stripped off and the product used without purification.

Workup

  1. additionThe temperature was kept at 10° to 20° C. during the addition
  2. customthe product used without purification

Sources & evidence

ORD record
ord-a24759284be844cda7ce7bc85599647c
Source dataset
uspto-grants-1983_05
Patent number
US04385104

Reaction notes

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