Triethylamine → HCID 54442060, compound

HRID 851654Notes

Reaction equation

HRID 851654 reaction equation
[CH3:1][O:2][C:3](=[O:21])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][NH:12][C:13]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=1.C(N(CC)CC)C.[Cl:29][C:30]1[CH:38]=[CH:37][C:33]([C:34](Cl)=[O:35])=[CH:32][CH:31]=1>CCOCC>[CH3:1][O:2][C:3](=[O:21])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][N:12]([C:13]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=1)[C:34](=[O:35])[C:33]1[CH:37]=[CH:38][C:30]([Cl:29])=[CH:31][CH:32]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 85014-Chlorobenzoyl chlorideHCID 13025816HCID 13025816, compound

Product 1

HCID 54442060HCID 54442060, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

As described in example 3(b) the reaction is carried out with 2 g. (6.8 mmol) of 9-(4-methoxyphenylamino)-pelargonic acid methyl ester, 0.75 g (7.5 mmol) of triethylamine, 1.2 g (6.8 mmol) of 4-chlorobenzoic acid chloride and 80 cc. of ether. The crude product is used in the next reaction step without further purification.

Sources & evidence

ORD record
ord-de3dec0f19244581bdfdd668c45244f3
Source dataset
uspto-grants-1983_05
Patent number
US04386031

Reaction notes

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