反应详情

As described in example 1(b), the reaction is carried out with 31.2 g (68 mmol) of 11-[4-chloro-N-(4-methoxyphenyl)-benzamido]-undecanoic acid methyl ester, 4.4 g (0.11 mol) of sodium hydroxide and 200 cc. of methanol. Reaction time: 15 hours, reaction temperature: 25° C. The crude product is further purified chromatographically on silicic acid gel using chloroform as eluant.

1. customReaction time
2. custom15 hours, reaction temperature
3. custom25° C
4. customThe crude product is further purified chromatographically on silicic acid gel