HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 11-[4-Chloro-N-(4-methoxyphenyl)-benzamido]-undecanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 11-[4-Chloro-N-(4-methoxyphenyl)-benzamido]-undecanoic acid methyl ester | HCID 53768777 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 11-[4-Chloro-N-(4-methoxyphenyl)-benzamido]-undecanoic acid | HCID 20500793 | — |
Reaction Steps
As described in example 1(b), the reaction is carried out with 31.2 g (68 mmol) of 11-[4-chloro-N-(4-methoxyphenyl)-benzamido]-undecanoic acid methyl ester, 4.4 g (0.11 mol) of sodium hydroxide and 200 cc. of methanol. Reaction time: 15 hours, reaction temperature: 25° C. The crude product is further purified chromatographically on silicic acid gel using chloroform as eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04386031 |
| Source dataset | uspto-grants-1983_05 |
| ORD ID | ord-c818c09ffdef4549a5730130134b1351 |
| Source note | uspto-grants-1983_05 |