Methanol → HCID 13025809, compound

Participants

Reaction Steps

As described in example 1(b), the reaction is carried out with 35 g (77 mmol), of 8-[2.4-dichloro-N-(4-methoxyphenyl)-benzamido]-caprylic acid methyl ester, 4 g (0.1 mol) of sodium hydroxide, 150 cc. of methanol and 5 cc. of water. Reaction time: 24 hours, reaction temperature: 25° C. The crude product is further purified chromatographically on silicic acid gel using a mixture of n-hexane and ethyl acetate (2:1) as eluant.

Provenance & Evidence