Methanol → HCID 20500781, compound

Participants

Reaction Steps

As described in example 1(b), the reaction is carried out with 15.8 g (38 mmol) of 8-[4-Chloro-N-(2.6-dimethylphenyl)-benzamido]-caprylic acid methyl ester, 2.2 g (55 mmol) of sodium hydroxide, 100 cc. of methanol and 5 cc. of water. Reaction time: 20 hours, reaction temperature: 25° C. The crude product is further purified chromatographically on silicic acid gel using chloroform as eluant.

Provenance & Evidence