Sodium Hydroxide → HCID 20500792, compound

Participants

Reaction Steps

As described in example 1(b), the reaction is carried out with 3.8 g (9 mmol) of 8-[2-chloro-N-(3-chlorophenyl)-benzamido]-caprylic acid methyl ester, 0.48 g (12 mmol) of sodium hydroxide and 50 cc. of methanol. Reaction time: 24 hours, reaction temperature: 25° C. The crude product is purified chromatographically on silicic acid gel using chloroform as eluant.

Provenance & Evidence