Sodium Hydroxide → HCID 20500790, compound

Participants

Reaction Steps

As described in example 1(b), the reaction is carried out with 8.6 g (16.8 mmol) of 8-{3.4.5-trimethoxy-N-[3-(trifluoromethyl)-phenyl]-benzamido}-caprylic acid methyl ester, 0.96 g (24 mmol) of sodium hydroxide and 100 cc. of methanol. Reaction time: 24 hours, reaction temperature: 25° C. The crude product is further purified chromatographically on silicic acid gel using chloroform as eluant.

Provenance & Evidence