HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-methylthiazole → HCID 58279251, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-methylthiazole | HCID 351770 | — |
| Reactant | 2-(4-(trifluoromethyl)pyridin-3-yl)-1H-benzo[d]imidazole-4-carboxylic acid | HCID 67201470 | — |
| Product | HCID 58279251 | HCID 58279251 | — |
Reaction Steps
2-(4-(Trifluoromethyl)pyridin-3-yl)-1H-benzo[d]imidazole-4-carboxylic acid 119 was coupled to 2-amino-5-methylthiazole 171 using the same general amide coupling procedure shown above to afford N-(5-methylthiazol-2-yl)-2-(4-(trifluoromethyl)pyridin-3-yl)-1H-benzo[d]imidazole-4-carboxamide (Compound 703). MS (ESI) calcd for C18H12F3N5OS: 403.07; found: 404 [M+H].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846947B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-110befc948534194af206c4d2cb77795 |
| Source note | uspto-grants-2014_09 |