Hydrochloric Acid → HCID 69507741, compound

Participants

Reaction Steps

Dry HCl gas was slowly bubbled through a solution of 4-chloro-N-(4-cyano-2-fluoro-benzyl)-N-((R)-2-oxo-azepan-3-yl)-benzenesulfonamide (0.09 g, 0.20 mmol) in dry ethanol (3 ml) for 30 min at 0° C. The reaction mixture wa allowed to stir for a further 20 h at r.t. and then concentrated under reduced pressure. Trituration of the residue in diethyl ether yielded the HCl salt: 0.09 g; MS: m/e=482.2 (MH+).

Provenance & Evidence